When
Thursday, 4 September 2008
Monday, 25 August 2008
Scientists Overcome Nanotech Hurdle
�When you make a new material on a nanoscale how can you see what you give made? A team spark advance by a Biotechnology and Biological Sciences research Council (BBSRC) mate has made a significant step toward overcoming this major challenge faced by nanotechnology scientists. With fresh research promulgated in ChemBioChem, the team from the University of Liverpool, The School of Pharmacy (University of London) and the University of Leeds, read that they have developed a proficiency to probe tiny protein molecules called peptides on the surface of a gold nanoparticle. This is the first time scientists have been able to build a detailed picture of self-assembled peptides on a nanoparticle and it offers the promise of new shipway to design and manufacture novel materials on the tiniest scale - one of the key aims of nanoscience.
Engineering new materials through assembly of complex, just tiny, components is hard for scientists. However, nature has become adept at engineering nanoscale building blocks, e.g. proteins and RNA. These are able to mannikin dynamic and efficient nanomachines such as the cell's protein assembly machine (the ribosome) and minute motors used for swimming by bacteria. The BBSRC-funded team, led by Dr Rapha�l L�vy, has borrowed from nature, developing a mode of constructing complex nanoscale building blocks through initiating self-assembly of peptides on the surface of a metal nanoparticle. Whilst this approach can provide a massive number and variety of new materials relatively easily, the challenge is to be able to examine the structure of the material.
Using a chemistry-based attack and information processing system modelling, Dr L�vy has been able-bodied to measure the distance between the peptides where they sit assembled on the au nanoparticle. The technique exploits the ability to differentiate between deuce types of connection or 'cross-link' - one that joins different parts of the same molecule (intramolecular), and some other that joins together deuce separate molecules (intermolecular). As two peptides get closer together there is a transition between the iI different types of connexion. Computer simulations allow the scientists to measure the distance at which this transition occurs, and thence to apply it as a sort of molecular ruler. Information obtained through this combination of chemistry and estimator molecular dynamics shows that the interactions between peptides leads to a nanoparticle that is relatively organized, but non uniform. This is the first time it has been possible to meter distances betwixt peptides on a nanoparticle and the first time computer simulations have been used to model a single bed of self-assembled peptides.
Dr L�vy aforesaid: "As nanotechnology scientists we face a challenge similar to the one faced by structural biologists half a century agone: determining the structure with atomic shell precision of a whole range of nanoscale materials. By victimisation a combination of chemical science and electronic computer simulation we have been able to demonstrate a method by which we can take off to see what is going on at the nanoscale.
"If we canful understand how peptides self-assemble at the surface of a nanoparticle, we tooshie open up a route towards the design and synthesis of nanoparticles that have complex surfaces. These particles could find applications in the biomedical sciences, for exercise to deport drugs to a particular target in the body, or to design raw diagnostic tests. In the longer term, these particles could likewise find applications in new generations of electronic components."
Professor Nigel Brown, BBSRC Director of Science and Technology, aforementioned: "Bionanotechnology holds expectant promise for the future. We may be able to create stronger, light and more durable materials, or unexampled medical applications. Basic science and techniques for functional at the nanoscale are providing the understanding that will permit future such applications of bionanotechnology."
Biotechnology and Biological Sciences Research Council
More info
Engineering new materials through assembly of complex, just tiny, components is hard for scientists. However, nature has become adept at engineering nanoscale building blocks, e.g. proteins and RNA. These are able to mannikin dynamic and efficient nanomachines such as the cell's protein assembly machine (the ribosome) and minute motors used for swimming by bacteria. The BBSRC-funded team, led by Dr Rapha�l L�vy, has borrowed from nature, developing a mode of constructing complex nanoscale building blocks through initiating self-assembly of peptides on the surface of a metal nanoparticle. Whilst this approach can provide a massive number and variety of new materials relatively easily, the challenge is to be able to examine the structure of the material.
Using a chemistry-based attack and information processing system modelling, Dr L�vy has been able-bodied to measure the distance between the peptides where they sit assembled on the au nanoparticle. The technique exploits the ability to differentiate between deuce types of connection or 'cross-link' - one that joins different parts of the same molecule (intramolecular), and some other that joins together deuce separate molecules (intermolecular). As two peptides get closer together there is a transition between the iI different types of connexion. Computer simulations allow the scientists to measure the distance at which this transition occurs, and thence to apply it as a sort of molecular ruler. Information obtained through this combination of chemistry and estimator molecular dynamics shows that the interactions between peptides leads to a nanoparticle that is relatively organized, but non uniform. This is the first time it has been possible to meter distances betwixt peptides on a nanoparticle and the first time computer simulations have been used to model a single bed of self-assembled peptides.
Dr L�vy aforesaid: "As nanotechnology scientists we face a challenge similar to the one faced by structural biologists half a century agone: determining the structure with atomic shell precision of a whole range of nanoscale materials. By victimisation a combination of chemical science and electronic computer simulation we have been able to demonstrate a method by which we can take off to see what is going on at the nanoscale.
"If we canful understand how peptides self-assemble at the surface of a nanoparticle, we tooshie open up a route towards the design and synthesis of nanoparticles that have complex surfaces. These particles could find applications in the biomedical sciences, for exercise to deport drugs to a particular target in the body, or to design raw diagnostic tests. In the longer term, these particles could likewise find applications in new generations of electronic components."
Professor Nigel Brown, BBSRC Director of Science and Technology, aforementioned: "Bionanotechnology holds expectant promise for the future. We may be able to create stronger, light and more durable materials, or unexampled medical applications. Basic science and techniques for functional at the nanoscale are providing the understanding that will permit future such applications of bionanotechnology."
Biotechnology and Biological Sciences Research Council
More info
Friday, 15 August 2008
Geri Halliwell strips for a bikini shoot
Washington (ANI): Spice Girls star Geri Halliwell has bared her stunning two-piece body for a aphrodisiac photo fritter in seven years, insistence that she's finally comfortable with her body. Throughout her life history, the 36-year-old has battled eating disorders, but is adamant that she is now fit and well after gift birth to her daughter Bluebell in 2006.
And in a new spread for British magazine Hello! the
And in a new spread for British magazine Hello! the
Thursday, 7 August 2008
Sixties Concert Discs Capture James Brown In His Prime
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Sixties Concert Discs Capture James Brown In His Prime -- Vulture -- Entertainment & Culture Blog -- New York Magazine
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Friday, 27 June 2008
50 Cent served restraining order by ex
50 Cent has been served with a restraining order that bars him from coming in contact with the mother of his 11-year-old son.
According to the Long Island, New York court order, the rapper must avoid all contact with Shaniqua Tompkins, and must pickup and drop off his son at curb-side during visitations.
The rapper, whose real name is Curtis Jackson, retaliated by filing a $20 million defamation suit and a petition holding Tompkins in contempt of court, reports E! Online.
Tompkins has alleged that 50 Cent is responsible for a fire last month that destroyed her residence -- the New York mansion they once shared. 50 Cent has vehemently denied the accusations.
--By our Los Angeles staff.
Find out more about NME.
According to the Long Island, New York court order, the rapper must avoid all contact with Shaniqua Tompkins, and must pickup and drop off his son at curb-side during visitations.
The rapper, whose real name is Curtis Jackson, retaliated by filing a $20 million defamation suit and a petition holding Tompkins in contempt of court, reports E! Online.
Tompkins has alleged that 50 Cent is responsible for a fire last month that destroyed her residence -- the New York mansion they once shared. 50 Cent has vehemently denied the accusations.
--By our Los Angeles staff.
Find out more about NME.
Monday, 23 June 2008
Louise Redknapp expecting second child
'The Clothes Show' presenter Louise Redknapp has announced that she is expecting her second child.
The 33-year-old television star said the news came as a shock because she had difficulty conceiving her first child due to a condition called endometriosis.
According to The Mirror, Redknapp said: "It was just absolute shock when I found out. It took me four years to have Charley and so this time, after just a month, it was very unexpected."
"We had talked about having another baby and we kind of expected the same problems as last time."
"When I did the pregnancy test, I nearly fell off the chair. The doctors don't know why it has been so much easier this time - it's just the luck of the draw I guess."
The television presenter has been married to former football player and pundit Jamie Redknapp. The couple already have a 3-year-old son.
The 33-year-old television star said the news came as a shock because she had difficulty conceiving her first child due to a condition called endometriosis.
According to The Mirror, Redknapp said: "It was just absolute shock when I found out. It took me four years to have Charley and so this time, after just a month, it was very unexpected."
"We had talked about having another baby and we kind of expected the same problems as last time."
"When I did the pregnancy test, I nearly fell off the chair. The doctors don't know why it has been so much easier this time - it's just the luck of the draw I guess."
The television presenter has been married to former football player and pundit Jamie Redknapp. The couple already have a 3-year-old son.
Monday, 16 June 2008
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